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- DOI 10.18231/j.ijpns.2025.014
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CrossMark
Atypical neurological decline in a teenager: A case of pantothenate kinase-associated neurodegeneration
- Author Details:
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Hardik Shah *
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Naiya Bhavsar
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Rajeshri Mehta
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Ashok Bhandari
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Nainesh Gorvadia
Hardik Shah *
Naiya Bhavsar
Rajeshri Mehta
Ashok Bhandari
Nainesh Gorvadia
Pantothenate Kinase-Associated Neurodegeneration (PKAN), formerly Hallervorden-Spatz disease, is a rare autosomal recessive neurodegenerative disorder characterized by progressive movement abnormalities and iron accumulation in the basal ganglia.
A 13-year-old male presented with a history of progressive gait disturbances, involuntary limb movements, and developmental regression. Imaging showed the pathognomonic "eye-of-the-tiger" sign in the globus pallidus. Supportive treatment was initiated.
This case demonstrates typical clinical and radiological findings of adolescent-onset PKAN. Early diagnosis can facilitate timely symptomatic intervention.
Keywords: Extrapyramidal sign, Hallervorden-Spatz disease, Dystonia, Dementia.
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