Pediatric Guillain-Barré Syndrome triggered by SARS-CoV-2: A case study and implications for post-viral neurological complications

• Author Details:   
• Hardik Shah ^*
• Naiya Bhavsar
• Lata Jha
• Ashok Bhandari
• Akshat Desai

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Guillain-Barré Syndrome (GBS) is a significant cause of acute, severe weakness in children, with Acute Inflammatory Demyelinating Polyradiculoneuropathy (AIDP) being the most common subtype. The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has been associated with various neurological manifestations, including GBS. We present the case of a 12-year-old male child who developed GBS after a past COVID-19 infection. Although the patient tested negative for SARS-CoV-2 via RT-PCR at the time of admission, he was positive for COVID-19 antibodies, suggesting a prior infection. The patient was treated with intravenous immunoglobulin (IVIG), with significant clinical improvement. This report highlights the potential association between COVID-19 and GBS in children and underscores the importance of recognizing post-infectious neurological complications.

Keywords: Extrapyramidal sign, Hallervorden-Spatz Disease, Dystonia, Dementia.